Season 1 Cast of the Series Samantha Who? (2007)
"Samantha Who?" cast
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Christina Applegate
Jennifer Esposito
Andrea Belladonna
Kevin Dunn
Melissa McCarthy
Dena
Tim Russ
Frank
Barry Watson
Jean Smart
Regina Newly
Soledad Campos
Jerry O'Connell
Rick Hoffman
Kiele Sanchez
Todd Grinnell
Jessica St. Clair
William Abadie
Joy Osmanski
Arshad Aslam
Timothy Olyphant
Rand Holdren
Gerald Downey
Johanna Braddy
Brett Rickaby
Beth Littleford
Eddie Cibrian
Curt Cornelius
Morgan Murphy
Nakia Burrise
Gerard Sanders
Frank Maharajh